Intellectual Property
Bioneer/siRNAgen Therapeutics Corporation owns a portfolio of patents and patent applications related to SAMiRNA™ technology, RNAi drugs/molecules for particular disease indications. siRNAgen Therapeutics Corporation’s SAMiRNA™ core technology and drug pipeline are protected within an extensive global intellectual property portfolio comprised of more than 90 patent applications and issued patents.
Patent
| Title | Country | Filing date | Application No. | Date of Patent | Patent No. |
| siRNA conjugate and preparation method thereof | KR | 2009-05-14 | 10-2009-042297 | 2013-01-16 | 1224828 |
| US | 2010-05-13 | 13/319,885 | 2014-07-15 | 8779114 | |
| Novel oligonucleotide conjugates and use thereof | PCT | 2012-12-14 | PCT/KR2012/010967 | ||
| High-efficiency nanoparticle-type double-helical oligo-RNA structure and method for preparing same | KR | 2013-01-04 | 10-2014-7018685 | 2017-06-26 | 1752812 |
| US | 2013-01-04 | 14/370,035 | 2016-05-03 | 9326941 | |
| Magnetic nanoparticle-samirna complex and method for preparing same | KR | 2013-01-17 | 10-2013-0005335 | 2016-06-03 | 1629233 |
| US | 2013-01-17 | 14/372,211 | 2017-05-16 | 9649388 | |
| Nanoparticle type oligonucleotide structure having high efficiency and method for preparing same | KR | 2014-07-04 | 10-2016-7001869 | 2018-05-23 | 1862349 |
| US | 2014-07-04 | 14/902,563 | 2018-07-24 | 10030243 | |
| Respiratory disease-related gene specific sirna, double-helical oligo rna structure containing sirna, compositon containing same for preventing or treating respiratory disease | KR | 2014-07-04 | 10-2016-7002234 | 2018-06-07 | 1867414 |
| EP | 2019-06-13 | 19180054.9 | 2019-10-16 | 3018209 | |
| Double-stranded oligo RNA targeted to amphiregulin and pharmaceutical composition comprising same for preventing or treating fibrosis or respiratory diseases | US | 2015-04-06 | 15/301,713 | 2019-02-19 | 10208309 |
| A double stranded oligonucleotide comprising Amphiregulin specific sequence and a composition for treating and preventing fibrosis related diseases and respiratory related diseases | PCT | 2019-05-22 | PCT/KR2019/006144 |
Publication
- Pyoung Oh Yoon, Jin Wook Park, Chang-Min Lee, Sung Hwan Kim, Han-Na Kim, Youngho Ko, Seon Joo Bae, Sungil Yun, Jun Hong Park, Taewoo Kwon, Woo Seok Kim, Jiyoung Lee, Qing Lu, Hye-Ryun Kang, Won-Kyung Cho, Jack A. Elias, Joo-Sung Yang, Han-Oh Park, Kyuhong Lee, and Chun Geun Lee, Self-assembled Micelle Interfering RNA for Effective and Safe Targeting of Dysregulated Genes in Pulmonary Fibrosis, J. Biol Chem, 291(12), pp. 6433-6446, 2016.
- Yang Zhou, Jae-Young Lee, Chang-Min Lee, Won-Kyung Cho, Min-Jong Kang, Jonathan L. Koff, Pyeong-Oh Yoon, Jeiwook Chae, Han-Oh Park, Jack A. Elias, and Chun Geun Lee, Amphiregulin, an epidermal growth factor receptor ligand, plays an essential role in the pathogenesis of transforming growth factor-β-induced pulmonary fibrosis, J. Biol Chem, 287(50), pp. 41991-42000. 2012.